KUF-13046 is a small molecule primarily identified as a research-grade biochemical tool. Based on current chemical abstract data and supplier specifications, KUF-13046 falls within a class of heterocyclic compounds known for their high binding affinity to specific G-protein coupled receptors (GPCRs) and enzyme families.
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The code does not refer to a widely recognized global object, but it aligns with the naming conventions used for technical components or logistics. Based on the most likely interpretations of "KUF": 1. Aviation & Travel (KUF: Samara Kurumoch International Airport In the travel industry, KUF is the IATA code for Kurumoch International Airport in Samara, Russia. KUF-13046
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A 2021 study in the Journal of Pharmacology and Experimental Therapeutics noted that administration of KUF-13046 in diet-induced obese (DIO) mice resulted in a over a four-week period. Furthermore, the compound improved insulin sensitivity without causing weight gain—a common side effect of many antidiabetic drugs.
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KUF-13046 is a synthetic small-molecule compound primarily studied for its role as a selective modulator of specific G-protein coupled receptors (GPCRs). GPCRs are the largest and most diverse group of membrane receptors in the human genome, and they are the target of approximately 34% of all FDA-approved drugs.
KUF-13046 appears to inhibit the oligomerization step of the NLRP3 complex. Unlike broad-spectrum anti-inflammatories (e.g., NSAIDs or corticosteroids), KUF-13046 leaves other immune pathways (like the NLRC4 or AIM2 inflammasomes) intact. This selectivity minimizes the risk of generalized immunosuppression—a common pitfall in drug development. Transition to 2D DataMatrix codes or standard QR
The hyphen serves as a visual and computational delimiter. It prevents scanning systems from misreading the code and helps human operators quickly differentiate between product classes and specific serial batches.
The compound is typically supplied as a lyophilized powder with a high-performance liquid chromatography (HPLC) purity rating often exceeding 98%, making it suitable for in vitro and in vivo preclinical studies. Its molecular weight sits within the "Lipinski Rule of Five" parameters, suggesting favorable oral bioavailability—a key characteristic for any viable drug candidate.